Daniel Ribes

Senior Health Economist

Bridging rigorous HEOR methodology with advanced analytics, engineering precision, and innovative technology solutions for healthcare decision-making.

10+
Years Experience
5
European Markets
6
Languages
2
Publications
DR
Economic Modeling Advanced Programming Market Access AI Integration

Professional Summary

Multidisciplinary expertise at the intersection of health economics, technology, and innovation

Senior Health Economist with 10+ years of experience leading teams in economic modeling, HTA submissions, market access, and pricing strategies across oncology, rare diseases, and cardiometabolic conditions.

Strong analytical expertise combining engineering, statistics, and econometrics with advanced programming skills (R, Python, Julia, VBA, C++). Proven track record in AI integration, blockchain development, and innovative healthcare solutions delivery.

Unique Professional Profile

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Health
Economist
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Agricultural
Engineer
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Blockchain
Developer

A rare intersection of domains enabling comprehensive understanding of technical, economic, and innovative healthcare challenges.

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International Experience

Worked and studied across Spain, UK, Switzerland, Netherlands, and Belgium, adapting to diverse healthcare systems.

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Innovation Leader

Pioneering AI integration and blockchain development for next-generation healthcare solutions.

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Proven Track Record

Successfully delivered HTA submissions for NICE, NCPE, SMC with major pharmaceutical clients.

Core Competencies

Technical skills and domain expertise spanning health economics and advanced technology

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Economic Modeling & HTA

Cost-Effectiveness Analysis (CEA), Budget Impact Models (BIM), and health technology assessment submissions for NICE, NCPE, and SMC.

  • Partitioned Survival Models
  • Markov Models & Decision Trees
  • Dynamic Transmission Models
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Survival & Statistical Analysis

Advanced survival analysis, parametric modeling, and complex statistical evaluations for clinical data interpretation.

  • Parametric Survival Extrapolation
  • Kaplan-Meier Analysis
  • Hazard Ratio Estimation
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Evidence Synthesis

Systematic literature reviews and Network Meta-Analysis (NMA) to support value propositions and comparative effectiveness.

  • Bayesian & Frequentist NMA
  • Indirect Treatment Comparisons
  • Real-World Evidence Analysis
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Pricing & Market Access

Comprehensive pricing strategies, reimbursement dossiers, and value communication tools for global markets.

  • Global Value Dossier Development
  • Pricing Negotiation Tools
  • Market Access Strategy
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Advanced Programming

Full-stack development capabilities applied to health economics modeling and tool creation.

R Python Julia VBA C++ WinBUGS
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AI & Blockchain Integration

Leveraging AI for process optimization and blockchain for secure, decentralized healthcare solutions.

  • AI-Driven Workflow Automation
  • Solidity & Hyperledger
  • Smart Contract Development

Professional Services

Comprehensive health economics and outcomes research solutions

01

HTA Submissions & Dossiers

Complete HTA submission support for NICE, NCPE, SMC, and other European agencies. Development of evidence-based value dossiers and reimbursement strategies.

βœ“ NICE Technology Appraisals βœ“ Global Value Dossiers βœ“ Payer Objection Handlers
02

Economic Modeling

Development of sophisticated cost-effectiveness models, budget impact analyses, and dynamic transmission models using state-of-the-art methodologies.

βœ“ Cost-Effectiveness Analysis βœ“ Budget Impact Models βœ“ Dynamic Transmission Models
03

Pricing & Market Access Strategy

Strategic pricing support and market access planning for pharmaceutical products across multiple markets and therapeutic areas.

βœ“ Pricing Strategy Development βœ“ Portfolio Pricing Models βœ“ Market Access Planning
04

Evidence Synthesis & Analysis

Systematic literature reviews, network meta-analyses, and real-world evidence studies to support clinical and economic value propositions.

βœ“ Network Meta-Analysis βœ“ Systematic Literature Reviews βœ“ Real-World Evidence
05

Advanced Analytics & AI Integration

Integration of artificial intelligence and machine learning to optimize healthcare analytics, automate workflows, and enhance decision-making.

βœ“ Process Automation βœ“ Predictive Analytics βœ“ AI-Driven Insights
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Custom Tool Development

Design and development of user-friendly, interactive tools for payer engagement, scenario analysis, and value demonstration.

βœ“ Excel/VBA Applications βœ“ Interactive Dashboards βœ“ R/Python Packages

Therapeutic Expertise

Deep knowledge across diverse disease areas

Oncology

Prostate Cancer, RCC, NSCLC, NETs

Rare Diseases

Cushing's Syndrome, Sickle Cell Disease

Vaccines

RSV, Infectious Disease Prevention

Autoimmune

Rheumatic Diseases, Biologics

MedTech

Cardiac Devices, PFO Closure

Cardiometabolic

Obesity, Diabetes, CVD

Featured Projects

Showcase of innovative health economics work

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Explore More on GitHub

Visit my GitHub profile to see additional portfolio projects, code repositories, and open-source contributions in health economics, blockchain, and AI integration.

πŸ”— View GitHub Portfolio

RSV Static Cost-Effectiveness Model

Model Developer

Collaboration with CHESS

Developed comprehensive static Cost-Effectiveness Model (CEM) and Budget Impact Models (BIM) tailored for multiple country adaptations.

Key Features:

  • Flexible architecture for diverse market localization
  • Clear ICER analysis and QALY estimation
  • Comprehensive scenario planning and sensitivity analysis
  • Integrated budget impact projections for payers
Excel VBA Static Modeling

NET Portfolio Budget Impact Model

HEOR Manager

Novartis Oncology, 2020-2021

Developed innovative portfolio approach for Neuroendocrine Tumors allowing flexible pricing strategies across multiple products.

Innovations:

  • Strategic pricing mechanisms with volume capping and portfolio discounts
  • Semi-defined matrix engine linking patient flow to survival data
  • Real-time scenario evaluation for payer negotiations
  • Adapted for Canadian and LATAM markets
VBA Engine Portfolio Strategy Budget Impact

Cushing's Syndrome Semi-Markov Model

Model Developer

Osilodrostat (LCI699) - Finland Setting

Sophisticated non-homogeneous semi-Markov cohort model to estimate cost-effectiveness of osilodrostat versus other treatments.

Technical Excellence:

  • Complex 262-state engine based on treatment history and response
  • User-friendly Executive UI for non-technical users
  • Scenario flexibility with "World WITH/WITHOUT" comparisons
  • Comprehensive tornado analysis and patient flow visualization
Excel/VBA Semi-Markov UI Design

Published Research

Peer-reviewed contributions to health economics literature

Kidney International Reports (2021)

Cost-Effectiveness Analysis of a Multi-Faceted Acute Kidney Injury Intervention Approach

Demonstrated the economic value and clinical impact of AKI interventions using a decision tree model, highlighting significant potential cost savings and improved patient outcomes through early detection.

View Article β†’
Current Medical Research and Opinion (2018)

Cost-Effectiveness Analysis of Paliperidone Palmitate for Schizophrenia in the UAE

Adapted a 1-year validated decision-tree model to the UAE setting to estimate cost-effectiveness of long-acting injectable antipsychotics vs. oral treatments, focusing on adherence advantages.

View Article β†’

Professional Journey

Career progression in health economics and innovation

2025

Engagement Manager

IQVIA | Barcelona (Remote)

Leading innovative projects with Core Obesity Model and integrated Obesity-Diabetes Model, coordinating teams on collaborative initiatives for improved patient outcomes.

2024-2025

HTA Modeler & AI Integration Lead

AXIS Consulting UK | Barcelona (Remote)

Coordinated HTA submissions for NICE, NCPE, SMC. Integrated AI solutions to streamline consultancy processes and improve operational efficiency.

2021-2024

Lead Modeler - Arexvy RSV

Freelance (GSK Project) | Barcelona (Remote)

Built comprehensive epidemiologic and pharmacoeconomic models for Arexvy vaccine, developing dynamic transmission models in Excel, VBA, R, and C++.

2020-2021

Region Europe HEOR Manager

Novartis Oncology | Basel, Switzerland

Supported country affiliates with HTA submissions, developed pricing commercial constructs, and established HEOR Centre of Excellence.

2018-2020

Health Economist Modeler Head

Wellmera AG | Basel, Switzerland

Published research in Kidney International Reports, developed pricing strategy models for Neuroendocrine Tumor treatments across multiple markets.

Education & Certifications

Academic foundation spanning economics, engineering, and technology

2024

Master in Blockchain Development

Codecrypto Academy, Madrid

Full Stack, DevOps, Solidity & Hyperledger

2017

Advanced Modelling Methods

University of York

Centre for Health Economics - Advanced economic evaluation techniques

2014-2015

MSc in Health Economics

City University of London

With Distinction

2005-2006

Management Development Program (PDD)

IESE Business School

Universidad de Navarra - Executive education

1986-1993

MSc in Agricultural Engineering

UPC & Wageningen University

Universitat Politècnica de Catalunya + ERASMUS Program

Language Proficiency

Spanish
Native
Catalan
Native
English
Fluent
French
Advanced
Italian
Advanced
German
Basic

Let's Connect

Discuss how I can support your market access goals

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Email

danribes@iies.es
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Phone

+34 696 62 83 77
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Location

Barcelona, Spain
(Remote-Ready)

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LinkedIn

Connect on LinkedIn
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GitHub

View Portfolio Projects
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Resume

Download CV

Ready to Collaborate?

I design and deliver robust, transparent HEOR models that inform critical pricing and access decisions. By combining deep health economics expertise with advanced analytics and software engineering, I accelerate evidence generation and operational efficiency for global healthcare partners.

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